Fosamax®

Fosamax (alendronate sodium), manufactured by Merck, is in a class of drugs called bisphosphonates.  Fosamax is commonly used in tablet form to prevent and treat osteoporosis in post-menopausal women.  Recently the Journal of Oral and Maxillofacial Surgeons reportd a link between bisphosphonates and a serious bone disease called Osteonecrosis of the Jaw (ONJ).

Osteonecrosis is a disfiguring and disabling condition of the jaw bone that causes infection and rotting of the jaw bone.  Typical presentation of Osteonecrosis is pain, soft-tissue swelling and infection, loosening of teeth, drainage, and exposed bone.  Symptoms may occur spontaneously, or at the site of previous tooth extraction.

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