Permax and Dostinex
Permax is a drug used for the treatment of Parkinson's Disease - a progressive neurological disorder resulting from the degenerastion of neurons in a region of the brain that controls movement.
Since its approval in 1989, Permax has been prescribed to more than 500,000 people for the control of tremors and restless leg syndrome.
In December 2002, cardiologists at the Mayo Clinic reported valvular heart disease in three clinic patients who had been taking Permax for several years.
This valvular heart disease found in these patients is similar to the damage found in patients who took the Fen-Phen/Redux diet drugs.
On April 28, 2004, results from a larger study performed by reasearchers from the University of Texas Southwest Medical Center found a threefold increased risk of heart valve damage among patients who used Permax.
Symptoms of valvular heart disease may include:
- Shortness of breath
- Chest pain
- Palpitations
- Fatigue
- Swelling of the feet and ankles
Some patients with valvular heart disease have no symptoms at all. An echocardiogram must be done to determine whether an individual suffers from abnormal valvular regurgitation.
Links with more information on Permax:
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