Premphase
Premphase is a hormone replacement therapy drug (HRT) prescribed for symptoms of menopause.
Approximately 6 million women are taking Premphase, a leading Hormone Replacement Therapy Drug, to treat post-menopausal hot flashes and other menopause symptoms. However, a recent major study concludes that long-term use of Premphase, is dangerous significantly increasing the risk of of stroke, blood clots, heart attacks and breast cancer.
These results were found in the nation's biggest hormone replacement study and were so alarming that the National Institute of Health (NIH) prematurely canceled the study citing risk to the study's participants. As a result the study suggested that many of the women who use Premphase and other estrogen and progestin combinations should quit and talk to their doctors about alternatives.
Premphase has been linked to the following side effects:
- dementia
- Alzheimer's disease
- stroke
- blood clots
- pulmonary embolisms
- lupus
- Breast cancer
The evidence is clear that Premphase and other estrogen progestin combinations can actually harm perfectly healthy women. Women taking Premphase have a 29% higher risk of heart attack, 41% higher risk of stroke and a 26% higher risk of breast cancer.
Another study released on May 27, 2003 adds to the health risks of hormone replacement therapy for post-menopausal women because it concludes the medications can double the risk of dementia and Alzheimer's disease.
Premphase is manufactured by Wyeth and it accounted for about $890 million of the company's $13.9 billion in sales in 2001.
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